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@physicaltherapyresearch
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906 Likes30 Comments

๐Ÿ“š๐Ÿ”ฌ
Oxygen-Ozone Injection for Knee OA
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INTRO:
Ozone (O3) gas is currently being injected to treat chronic pain relief in knee osteoarthritis (OA)
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Injected O3 gas, is thought to improve pain and function in Knee OA through inhibition of the inflammatory process.
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Sconza et al. (2019), systematically reviewed RCTโ€™s, in the past 20 years, covering ozone intra-articular injection for the treatment of Knee OA. .
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RESULTS:ย 
11 studies
858 patients (629 female and 229 male).
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Control groups included:
+Placebo (1 trial)
+Hyaluronic acid injection (2 studies)
+Hyaluronic acid & PRP injection (1 trial) +Corticosteroid injection (4 studies)
+Hypertonic dextrose, Radiofrequency, or Celecoxibย + Glucosamine (3 trials). .
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Quality of Studies:
Cochrane Risk of Bias Tool was Used
Good - 0
Fair - 2
Poor - 9 .
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No major complications or serious adverse events were reported.
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Encouraging pain relief at short-term. .
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Encouraging pain relief mid-term.
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On the basis of the available data, no clear indication emerged from the comparison with other established treatments for Knee OA.
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CONCLUSIONS:
Available research is of poor methodological quality.
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Most studies flawed by relevant bias.
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On the basis of the data available:
+Can be a safe approach
+Encouraging pain control and functional recovery in the short/middle term.
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Thoughts? Questions? Comments?
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Write them below. .
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SOURCE:
Sconza et al. 2019. Oxygenโ€“Ozone Therapy for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials. Arthroscopy.

17 Nov 2019

Comments
  • @sambovich

    @_karemebrahim

    12 Jan 2020

  • @raelynn.jalbert

    @jay7day

    18 Nov 2019

  • @dr.dchatim.physio

    @orthodoc_alhad thoughts ??

    18 Nov 2019

  • @vinacastro

    @guipellucci ๐Ÿ‘€

    18 Nov 2019

  • @physioestelle

    WTF - any less toxic than cortisone.. Any more helpful? What next.... ๐Ÿ˜

    17 Nov 2019

  • @_a_r_p_106

    After therapy from how much time after physiotherapy treatment should be started???

    17 Nov 2019

  • @jttheat

    Got anything on ankles? Crushed my talar dome recently.

    17 Nov 2019

  • @amr.hesham.mousa

    @m_7amoda

    17 Nov 2019

  • @alfy_son

    Chemically speaking ozone sounds like a horrible treatment. It will oxidize and destroy the cells it touches. Yeah less pain because you just killed everything in there

    17 Nov 2019

  • @synergywp

    @regenerativeperformance Thoughts?

    17 Nov 2019

  • @stevenheat

    Can it help the scar tissue buildup as a result of acl surgery? Currently back in pt 2 years after acl reconstruction, because of scar tissue issues around acl graft๐Ÿ˜ž This is even after I followed the pt after acl surgery religiously!

    17 Nov 2019

  • @thebodytuner

    I've solved hundreds of cases of severe knee OA using only manual manipulation. This sounds like another temporary avoidance strategy for people who don't know their knee can be fixed with the hands. Injections are great for getting closer to surgery. They buy you more time without actually addressing any of the root causes of musculoskeletal dysfunction. If injections were legally paired with hands on therapy they would make more sense but most people get an injection and then call it a day for a month until the pain returns.

    17 Nov 2019

  • @ana_ckds

    Me lo pusieron y no sirviรณ para nada

    17 Nov 2019

  • @elpappichino

    @zachbailowitzmd @columbiadancemedicine @jeubanksmd @marcbronson.dc @mikereinold

    17 Nov 2019

  • @eggenhysenii

    Well is it better than using cortisone injection?

    17 Nov 2019

  • @omarlbaba

    Can u tell me more about it ??

    17 Nov 2019

  • @frankie_vondutch

    @gault.lydia

    17 Nov 2019

  • @physicaltherapyresearch

    . . . #rehab #pain #painscience #physiology #physicaltherapy #physiotherapy #massage #orthopedic #chiropractic #medicine #sportsmedicine #science #research #health #wellness #nervoussystem #neuroscience #brain #physicaltherapyresearch #dpt #dptstudent #exercise #fitness #workout #o3therapy

    17 Nov 2019